10 Best Acne Spot Treatments in 2023 [Effective & Powerful]


Acne spot treatments are skincare products that are designed to target and treat individual pimples or blemishes on the skin. They are typically applied topically to the affected area, and work by reducing inflammation, unclogging pores, and killing the bacteria that cause acne.

Best Overall
1
4.9
Mighty Patch Invisible Hydrocolloid Acne Spot Treatment

Mighty Patch Invisible Hydrocolloid Acne Spot Treatment

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Best Runner-Up
2
4.8
Rael Acne Pimple Healing Patch

Rael Acne Pimple Healing Patch

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  • MADE WITH HIGH-GRADE HYDROCOLLOID: Adhere directly to the skin and extract all the pus and impurities straight from the source.
  • "MFD" (Date of Manufacturing) - The date on the back of the package stands for Manufactured Date, not expiration date.
  • TRANSPARENT: Invisible so you can feel confident wearing the patches in bright sunlight.
  • STRONG ADHESIVE: Effective even on those pesky pimples that haven't surfaced! The Healing Patch will calm, flatten and soothe your skin
  • TWO SIZES: A single pack includes 24 total patches including two sizes:10mm (12 patches)12mm (12 patches)
Best Exfoliating
3
4.7
ZitSticka Killa Acne Pimple Patch Kit

ZitSticka Killa Acne Pimple Patch Kit

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  • FOR HARD-TO-REACH ZITS: ZitSticka's KILLA patch is unlike standard hydrocolloid zit patches. It goes beyond the surface to target those stubborn, emerging pimples that can be hard to reach. While flat hydrocolloid patches work well for superficial issues, KILLA is designed to tackle up-and-coming zits effectively.
  • EX-ZIT STRATEGY: With ZitSticka's signature microdart delivery system, we don't wait for the blemish to fully form. KILLA accesses the source of the zit, allowing its potent ingredients to take action in the 'upcoming' stage. This means we can swiftly curb the pimple's progress or bring it quickly to the surface, where it can be easily managed.
  • HIGHLY EFFECTIVE, QUALITY INGREDIENTS: Once the 24 (pain-free!) microdarts dissolve, a synergistic potion of hyaluronic acid, salicylic acid, niacinamide and oligopeptide-76 flood the heart of an early-stage zit, blocking it from reaching its potential.
  • DERMATOLOGIST-BACKED PREMIUM INGREDIENTS: KILLA combines cutting-edge technology with skincare expertise, featuring a synergistic blend of hyaluronic acid, salicylic acid, niacinamide, and oligopeptide-76 that are dermatologist-backed to precisely target your breakout-prone areas. This formula ensures that early-stage blemishes don't reach their full potential.
  • KIT INCLUDES: The KILLA 8-pack includes 8 microdart KILLA patches and 8 priming CLEANA swabs to prepare the blemish before patch application. Rest assured, the KILLA Kit is Vegan and Cruelty-Free, aligning with your commitment to ethical skincare choices.
Best Cruelty Free
4
4.6
Acnecide Spot Treatment Benzoyl Peroxide

Acnecide Spot Treatment Benzoyl Peroxide

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  • LEAVE-ON MEDICINAL TREATMENT: Treat mild acne or recurring breakouts to help break the cycle of spots; helps unblock pores to reduce blackheads and whiteheads
  • ACTIVE INGREDIENT: Contains 5 percent benzoyl peroxide; clinically proven to target and reduce spot-causing bacteria by up to 95 percent in 1 week
  • EFFECTIVE HYDRATION : Contains "AC Microsphere Technology" which helps absorb excess oil while releasing glycerine to soothe the skin
  • FOR DAILY USE: Apply up to once or twice daily to affected areas after cleansing; avoiding sensitive areas such as the eyes, mouth, nose lining and neck. ALWAYS READ THE LABEL
  • COMPLETE YOUR SKIN-CONFIDENT ROUTINE: Use with Purifide Daily Cleanser and Microbiome Equalizer
Best Organic
5
4.5
Super Facialist Breakout Buster Serum

Super Facialist Breakout Buster Serum

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  • SERUM: This spot treatment serum with super facialist skin balancing complex helps improve hydration, minimise skin dryness & boost skin barrier function - effective face care
  • 10% NIACINAMIDE: Dermatologically tested serum with Vitamin B 3 helps reduce the appearance of oily skin, minimise redness & works as a great acne treatment
  • TEA TREE OIL: Organic Tea Tree is antimicrobial to help minimise the appearance of breakouts & gives this. serum a fresh scent
  • PREBIOTICS: Prebiotics from Chicory are added to this face cream to keep your skin balanced & prevent spots - gentle skincare
  • SKINCARE SET: Pair this spot treatment serum with Super Facialist Clear Skin Daily Moisturiser & upgrade your skincare routine - makes a fabulous gift set idea
Best Natural
6
4.4
Glycolic/Salicylic Acid 10/2 Acne Control Pads

Glycolic/Salicylic Acid 10/2 Acne Control Pads

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  • ACNE CONTROL PADS – These pads come fully saturated with a solution containing 10% of pure Glycolic Acid and 2% of medical-grade Salicylic Acid. They unclog pores, control sebum generation and exfoliate the skin, limiting the potential for breakouts and leaving the skin looking clearer and healthier.
  • BOOSTED WITH VITAMINS B5, C & E – Powerful antioxidants that will leave your skin fully hydrated and that will help repair photo-damage from UV rays.
  • CONTAINS ALLANTOIN AND GREEN TEA & CALENDULA EXTRACTS – Allantoin helps to soothe and protect the skin while Green Tea and Calendula extracts act as anti-inflammatory and antioxidant agents.
  • PROFESSIONAL NON WOVEN TEXTURED PADS – Each jar comes with 50 professional-grade non woven textured pads with a convenient finger notch for easy application.
  • QRxLabs products are Made in the USA in an FDA-registered facility. We only use professional-grade ingredients and never any silicone or parabens. We also take pride in our cruelty-free practices and eco-friendly packaging. All QRxLabs products are covered by our Total Satisfaction so you can purchase and use our products with confidence.
Best Durability
7
4.3
BeBarefaced Anti Blemish Treatment

BeBarefaced Anti Blemish Treatment

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  • Put spots to bed with this natural overnight treatment gel. Just a dab of this blemish-busting formula instantly helps speed up the healing process and reduce redness. Very gentle, never drying or irritating and perfect for sensitive skin.
  • Unfortunately spots occur for many reasons; stress, hormones and diet to name but a few! While our anti blemish overnight gel can’t correct these external factors and vanish spots forever more (if only!) You can rely on it as a helpful tool to get spots healing fast!
  • Organic seaweed works to fade scars and imperfections, reducing discolouration. While organic aloe vera minimises swelling. Enriched with antibacterial botanicals geranium and cistus to sooth irritation and sanitise skin encouraging a clearer complexion.
  • Formula absorbs deep into the skin while you sleep. Wake up to reveal a Barefaced confidence with spots and blemishes calmed and reduced.
  • 30 day money back guarantee. Check out our images for multi-buy discounts! Packaging may vary.
Best Hydrating
8
4.2
Clearly ZITS Natural Acne Spot Treatment

Clearly ZITS Natural Acne Spot Treatment

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  • ✔ PLANT-BASED FORMULA - 100% natural with Tea Tree and Lemon essential oils to help conceal, dry and heal pimples + Aloe Vera and Almond oils to protect your skin from dryness and irritation. No chemicals, alcohols, preservatives or harsh ingredients. Vegan and Cruelty Free. Made in the USA.
  • ✔ GENTLE AND HYDRATING - Whether your skin is oily, dry or a combination, Clearly ZITS is effective for all skin types as it helps to balance oil production, soothe irritation, hydrate and maintain your skin's natural moisture. Effective against acne yet gentle enough for the most sensitive skin.
  • ✔ DOES NOT CLOG PORES - A non comedogenic formula helps to clear the pores to eliminate excess oil and blackheads, preventing future breakouts, acne scars and improving your skin's texture and appearance.
  • ✔ PREVENTS FUTURE BREAKOUTS - Use as a spot treatment to help clear existing acne and as an all over face serum to help prevent skin congestion and future breakouts. Effective against mild, moderate, teen, adult, cystic, hormonal and severe acne. A natural, effective, and better-for-your-skin alternative to glycolic acid, salicylic acid, sulfur and benzoyl peroxide.
  • ✔ ROLL-ON APPLICATOR - A stainless steel roll-on applicator makes it easy to apply to your face - no cotton needed and no touching your face while applying. Easy and convenient!
Best Non Greasy
9
4.1
Ivnil Anti Acne Spot

Ivnil Anti Acne Spot

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  • [EFFECTIVE & POWERFUL NATURAL ACNE CREAM FOR FACE & BODY] Acne cream is made of all natural ingredients, the main active ingredient, It is rich in Salicylic Acid & Aloe Vera & Tea Tree Oil, which has the function of anti-inflammatory and pain-relieving. It can soften the acne skin, improve skin smoothness and gently exfoliating the acne area. Other ingredients will help moisturize, repair the damaged skin, reactivate the skin cell and renew the skin.
  • [ACNE AND PREVENTION] Our acne face cream contains natural cruelty-free ingredients that help unblock sebaceous glands, tighten pores while locking in needed moisture. This helps in balancing oil production for eliminating skin impurities.With continued use, this acne moisturizer will leave your skin feeling smooth.
  • [NOT GREASY, NON COMEDOGENIC & ABSORBS EASILY]This acne for face is not going to cause more breakouts as other acne face creams, without causing rashes or irritation- formulated to keep you moisturized while helps you to get rid of acne.Dermatologically & Allergy tested & Non-irritating.
  • [FOR EVERY TYPE OF SKIN - EVEN SENSITIVE]Acne for sensitive skin and any other types of skin. Specially formulated not to clog pores and be gentle while maintaining maximum effectiveness.Gentle, Paraben Free, and Fragrance Free skin care to avoid irritation on acne-prone skin.Suitable For Face, Back, Inner Thigh And Buttock.
  • [100% SATISFACTION GUARANTEED]If you have any product-related issues, please contact us and we'll immediately make everything right for you within 24 hours! Customer service and satisfaction are always our top priority.Our Acne Cream with a 60-Day Unconditional Full Money Back Guarantee, so you can purchase with confidence!
Cheapest Option
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4
Dots for Spots Acne Patches

Dots for Spots Acne Patches

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  • THE REAL DEAL - The one-step, easy to use, innovative and effective way to target your acne. Hydrocolloid patches create a moist environment and optimum conditions for your spot to heal.
  • ULTRA-THIN AND TRANSLUCENT - Each one of our mighty zit patches is translucent, ultra-thin, and has tapered edges to seamlessly blend with all skin tones so you can proudly wear them day or night.
  • VISIBLE RESULTS - Dots for Spots pimple patches act as a protective cover to prevent picking, touching or popping, while also working to minimize the appearance of redness and active breakouts.
  • PROMOTES FASTER HEALING - For best results, wear for 6+ hours, or simply leave on overnight. You can tell the pimple patch is ready to be removed when the translucent center has turned opaque white.
  • NO HIDDEN INGREDIENTS - Our spot dots are vegan, non-irritating, and fragrance, alcohol, paraben, and phthalate free - making them safe and suitable for all skin types, tones and textures!


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